
Max Shen
Debug Your Pain
What if pain isn’t really a signal of tissue damage but rather a speculative prediction the body has learned to make, which can be unlearned?
Read moreExpeditions is an experimental fund built around the idea of interestingness, a central theme in Why Greatness Cannot Be Planned: The Myth of the Objective by Kenneth Stanley and Joel Lehman. We look for independent researchers, amateur inventors, and others following ideas that feel promising, even if their purpose is not yet defined.
How do breakthroughs happen? When we track the origins of scientific discoveries, a pattern becomes clear: the right person, in the right place, at the right time, decides to pursue what sparked their curiosity.
But that's the lucky case. We rarely hear about the times when the opportunity existed, but the person was unable to follow their hunch.
Expeditions exist to reclaim these lost opportunities and give them a proper home.
Our job is to recognize potential and help it materialize.
Read more about our process, philosophy, and Frequently Asked Questions.
Here are the Expeditions we have supported. This includes exploratory work as well as retroactive awards for curiosity-driven efforts.

Debug Your Pain
What if pain isn’t really a signal of tissue damage but rather a speculative prediction the body has learned to make, which can be unlearned?
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Material Farming
What if we could simply grow the materials we need, without toxic chemicals or genetic engineering?
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Homunculus
While everyone is busy chasing artificial intelligence, why don’t we learn how to communicate with biological intelligence directly instead?
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Theory of Vasocomputation
Unifying Buddhism, phenomenology, and neuroscience into an elegant account of why body and mind were never separate to begin with.
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Live Longer World
Everyone wants to be healthier; almost no one has time to parse through the snake-oil in health and longevity.
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Conditions of We
Trust is more scarce than we like to think. And yet, our ability to coordinate depends on it. How does trust emerge and when does it break down?
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Folk Science
What if your rare medical problem has already been solved and documented in some obscure Reddit thread buried at the bottom of the Internet?
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The Library of Consciousness
A curated vault of 1,000+ rare, weird texts exploring one big idea: that the universe is waking up to itself.
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Niche Design vol. 2
Examining the rise of pseudoanonymity as a vehicle for culture-making.
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The Space Between
Investigating the mechanism behind rouleaux (red blood cell clumping) and the role of structured water in human vitality.
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Open Memetics
Decoding how ideas travel and take root online — so more people can coordinate consciously and at scale.
Read moreThey aren't all necessary, but the more, the merrier.
It's “likely to reveal large and unexpected portions of the map.”
It feels like someone should work on this.
You're uniquely positioned to work on it.
Genuinely intriguing, not just different for the sake of it.
You have already made some steps in the direction or making it real.
Knowledge wants to be free. There is some way to share your findings with others.
By definition, if it fits nicely into existing categories, then it isn't really new.
Even if it fails, we learn something from it.
There exists a realistic way to verify it without burning lots of resources.
Do we have a match? Apply or read Frequently Asked Questions first.
We welcome ideas from any field, including those that do not yet have a field to belong to. That said, here are some of the themes we’re currently exploring. If your project fits one of them, we may already be on the same page.
Metabolic theory of health · Health as systems and energy, not just biomedicine · Alternative paradigms of health · Bioenergetics · Non-allopathic paradigms of health · Salutogenesis · Positive paradigms of health · Preventative medicine · Eudaimonia · Polyvagal theory · The energy-centric perspective
Deception studies · Adversarial epistemology · Developing a healthy relationship with media and technology · Information hygiene · Conscious consumerism · New Literacy · Recognizing scams, propaganda, misinformation, and other deceptive practices
Deschooling · Unschooling · Home schooling · Education for adults · New Literacy · Developmental theory · Learning to learn · Self-directed learning systems · Peer-to-peer universities
Investigatingating direct experience · Study of subjective experience · Psychotechnologies · Phenomenology · Nootropics · Obscure psychedelics · Contemporary contemplative practice · Jhānas · Fetters
Organizational design · Alternative dispute resolution methods · Game theory of voluntary cooperation · Conversational protocols that prevent coercion · Voluntaryism
Recognizing types of brilliance different than yours · Translating between cognitive styles · Neurodivergence-friendly workplace · Nonverbal thinking styles · Polymathic systems thinkers · “Schizo-autists” · Heterodox thinkers · Modern polymaths · Systemic fluid intelligence
Theory of mind · Collaborative problem-solving · Finding compatible collaborators · Game theory of cooperation · Constructive conflict
Electroculture · Grounding · Mind-body connection · Bioelectricity · Placebo · EMF · Bioelectric theory of cancer · Plasma physics · Alternative paradigms of health
Fixing health hazards of modern lifestyle · Healthy artificial lights · Sourcing your own food · Neo-tribalism · Functional movement · Myth, ritual, and symbolic technology · History of early humans · Lindy solutions
N=1 experiments · Personal science methodology · Personal health · Self-experimentation · Shulginism · Personal diagnostics · Citizen science · First-person science · Mystery disease · Rare disease · Integrating soft evidence · Edge‑of‑science topics where formal research and folk practice overlap
Privacy tech and protocols · Peer-to-peer networks · Censorship-resistant technology · Anti-surveillance · Investigative journalism · Local-first software · Open Source Intelligence · Trust-minimized collaboration tools · Trust chains
Things with both practical leverage and philosophical bite · Heuristics for navigating fringe claims without going woo or cynic · "Research is to see what everybody else has seen, and to think what nobody else has thought." — Albert Szent-Gyorgyi
Research palette for Spring/Summer 2026
“Sovereign, cooperative humans in complex systems, grounded in body and experience, using both fringe and rigorous tools.”
We find them, you fund them. Help us convert capital into discovery by becoming a patron.
Releasing trauma with 2C‑B, an obscure party drug
Releasing trauma with 2C‑B, an obscure party drug
Can 2C‑B, Alexander Shulgin's "Great Teacher" be a force multiplier for Trauma-Releasing Exercise (TRE)?
Discovering Censored Science
Discovering Censored Science
Discover censored scientific papers by having AI agents examine references between publications.
Psilocybin and paralysis
Psilocybin and paralysis
Investigate anecdotal reports of psilocybin restoring movement in paralyzed patients—and search for a reproducible mechanism.
Cracking endometriosis
Cracking endometriosis
Testing safe dietary and lifestyle interventions designed to reverse endometriosis without surgery based on the metabolic theory of health.
Using psychedelics to reverse allergies
Using psychedelics to reverse allergies
Reversing allergies and autoimmune disorders through psychedelics-induced neuroplasticity.